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The review reports inclusion and exclusion criteria clearly, searched a good group of databases for studies published over a long period of time and the authors ensured screening and data extraction was undertaken by multiple independent team members. However, minor limitations include the fact that bias ratings for each bias criterion were not reported, and that results are not reported and analysed separately by risk of bias status. There’s no in-depth discussion of differences in results between studies or what factors may have led to the differences. Also of concern is that meta-analysis was undertaken and not reported because of high I2. One major limitation is for the search with inclusion restricted to studies in English and Spanish and no indication that reference lists or experts were consulted.