Preventing HIV and HSV-2 through improving knowledge and attitudes: a replication study of a multicomponent intervention in Zimbabwe

3ie Replication paper 16

Fang Yu, Nicholas A Hein and Danstan S Bagenda

Yu and colleagues conducted a replication study of an influential paper “The Regai Dzive Shiri Project: results of a randomised trial of an HIV prevention intervention for Zimbabwean youth” by Frances Cowan and colleagues. The original study investigated a community-based, multicomponent HIV and reproductive health intervention aimed at young people in rural Zimbabwe. Despite some changes in knowledge, attitudes, and reduced prevalence of pregnancy, the original publication found that community-based interventions did not affect the prevalence of HIV or HSV-2 in this context.

The replication authors performed a push button replication and a pure replication that generally replicated the original results with few minor discrepancies. They also conducted a theory of change analysis to supplement the original analyses by assessing whether an increase in knowledge or attitudes or a combination of both is associated with a decrease in the prevalence of HIV or HSV-2. They further examined the robustness of the original results using measurement and estimation analyses. The results showed that the demographics of the study population changed over time and participants received different amounts of exposure to the intervention. The amount of exposure to the intervention affected knowledge and attitude outcomes and a few risky sexual behaviors. The replication authors concluded that it could be useful to design an intervention that maximizes the amount of intervention exposure received by the participants, and explore additional and/or complementary interventions with a focus on reducing risky sexual behaviors for HIV or HSV-2 prevention.

3ie Replication paper 18

Savings revisited: a replication study of a savings intervention in Malawi

Replication paper 3ie 2018

Jesper Stage and Tharshini Thangavelu replicate the results of a randomized evaluation carried out by Lasse Brune and colleagues in 2016 in Malawi.


Mobile money and its impact on improving living conditions in Niger: a replication study

Replication paper 3ie

Edmundo Beteta and colleagues replicate the results of a randomized evaluation carried out by Aker and colleagues in 2016 in Niger.

3ie Replication Paper 17

Thou shalt be given... but how? A replication study of a randomized experiment on food assistance in northern Ecuador

Replication paper 3ie 2018

Lhachimi and Seuring re-examine the results of a cluster-randomized evaluation carried out by Melissa Hidrobo and colleagues in 2013 in two provinces in northern Ecuador.


When to start ART? A replication study of timing of antiretroviral therapy for HIV-1-associated Tuberculosis

Replication paper 3ie 2018
In this paper, the research team conducted a replication study of Havlir and others’ 2011 study, “Timing of antiretroviral therapy for HIV-1 infection and tuberculosis.”


Stretching HIV treatment: A replication study of task shifting in South Africa

Replication paper 3ie 2017
Baojiang Chen and Morshed Alam conducted a replication study of Fairall and other’s influential paper, “Task shifting of antiretroviral treatment from doctors to primary-care nurses in South Africa (STRETCH)”.