Stretching HIV treatment: A replication study of task shifting in South Africa

3ie Replication paper 13

Baojiang Chen and Morshed Alam

Baojiang Chen and Morshed Alam conducted a replication study of Fairall and other’s influential paper, “Task shifting of antiretroviral treatment from doctors to primary-care nurses in South Africa (STRETCH)”. The original study examined a critical challenge to widespread HIV treatment in South Africa by conducting a cluster-randomised evaluation to determine the efficacy of the Streamlining Tasks and Roles to Expand Treatment and Care for HIV (STRETCH) programme on patient health outcomes. The original authors found that STRETCH did not decrease the mortality rate as compared to standard care. The intervention was more effective than the standard care system in patients with CD4 counts of 201-350 cells/µL as compared to patients with CD4 counts of 200 cells/µL or fewer. Although, the proportion of STRETCH patients with an undetectable viral load one year after enrolment was equivalent to that among the control patients.

In this replication study, the researchers conducted push button, pure, and measurement and estimation analyses. Although they find some minor differences between the published results, they generally replicated the published findings.

3ie Replication paper 18

Savings revisited: a replication study of a savings intervention in Malawi

Replication paper 3ie 2018

Jesper Stage and Tharshini Thangavelu replicate the results of a randomized evaluation carried out by Lasse Brune and colleagues in 2016 in Malawi.


Mobile money and its impact on improving living conditions in Niger: a replication study

Replication paper 3ie

Edmundo Beteta and colleagues replicate the results of a randomized evaluation carried out by Aker and colleagues in 2016 in Niger.

3ie Replication Paper 17

Thou shalt be given... but how? A replication study of a randomized experiment on food assistance in northern Ecuador

Replication paper 3ie 2018

Lhachimi and Seuring re-examine the results of a cluster-randomized evaluation carried out by Melissa Hidrobo and colleagues in 2013 in two provinces in northern Ecuador.


Preventing HIV and HSV-2 through improving knowledge and attitudes: a replication study of a multicomponent intervention in Zimbabwe

Replication paper 3ie 2018
Yu and colleagues conducted a replication study of an influential paper “The Regai Dzive Shiri Project: results of a randomised trial of an HIV prevention intervention for Zimbabwean youth” by Frances Cowan and colleagues.


When to start ART? A replication study of timing of antiretroviral therapy for HIV-1-associated Tuberculosis

Replication paper 3ie 2018
In this paper, the research team conducted a replication study of Havlir and others’ 2011 study, “Timing of antiretroviral therapy for HIV-1 infection and tuberculosis.”