Baojiang Chen and Morshed Alam conducted a replication study of Fairall and other’s influential paper, “Task shifting of antiretroviral treatment from doctors to primary-care nurses in South Africa (STRETCH)”. The original study examined a critical challenge to widespread HIV treatment in South Africa by conducting a cluster-randomised evaluation to determine the efficacy of the Streamlining Tasks and Roles to Expand Treatment and Care for HIV (STRETCH) programme on patient health outcomes. The original authors found that STRETCH did not decrease the mortality rate as compared to standard care. The intervention was more effective than the standard care system in patients with CD4 counts of 201-350 cells/µL as compared to patients with CD4 counts of 200 cells/µL or fewer. Although, the proportion of STRETCH patients with an undetectable viral load one year after enrolment was equivalent to that among the control patients.
In this replication study, the researchers conducted push button, pure, and measurement and estimation analyses. Although they find some minor differences between the published results, they generally replicated the published findings.
The authors of this paper replicated a landmark study by Hayes and colleagues (2019) on the HPTN 071 (PoPART) trial, which examined if a universal test and treatment program, along with a combination prevention intervention, could reduce HIV incidence in Zambia and South Africa.
Eric Djimeu and Eleanor G Dickens conduct a replication of the HPTN 052 study by Cohen and colleagues that evaluates the impact of early initiation of antiretroviral therapy on rates of sexual transmission of HIV-1.
The National Rural Employment Guarantee Scheme and Social Security Pension are two of the largest employment programmes in Andhra Pradesh. Muralidharan and colleagues (2016) investigated the impacts of biometrically-authenticated payment infrastructure (Smartcards) on beneficiaries of the two employment programmes.
This replication study starts with the twin strategies of push-button and pure replications of the original study. It then followed this up with various consistency and
robustness checks, such as propensity score matching and the Tobit model specification.