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Replication papers
RP16

Preventing HIV and HSV-2 through improving knowledge and attitudes: a replication study of a multicomponent intervention in Zimbabwe

3ie Replication paper 16

Fang Yu, Nicholas A Hein and Danstan S Bagenda

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Yu and colleagues conducted a replication study of an influential paper “The Regai Dzive Shiri Project: results of a randomised trial of an HIV prevention intervention for Zimbabwean youth” by Frances Cowan and colleagues. The original study investigated a community-based, multicomponent HIV and reproductive health intervention aimed at young people in rural Zimbabwe. Despite some changes in knowledge, attitudes, and reduced prevalence of pregnancy, the original publication found that community-based interventions did not affect the prevalence of HIV or HSV-2 in this context.

The replication authors performed a push button replication and a pure replication that generally replicated the original results with few minor discrepancies. They also conducted a theory of change analysis to supplement the original analyses by assessing whether an increase in knowledge or attitudes or a combination of both is associated with a decrease in the prevalence of HIV or HSV-2. They further examined the robustness of the original results using measurement and estimation analyses. The results showed that the demographics of the study population changed over time and participants received different amounts of exposure to the intervention. The amount of exposure to the intervention affected knowledge and attitude outcomes and a few risky sexual behaviors. The replication authors concluded that it could be useful to design an intervention that maximizes the amount of intervention exposure received by the participants, and explore additional and/or complementary interventions with a focus on reducing risky sexual behaviors for HIV or HSV-2 prevention.

Treatment as Prevention: A replication study of a universal test and treatment cluster-randomized trial in Zambia and South Africa

Treatment as Prevention: A replication study of a universal test and treatment cluster-randomized trial in Zambia and South Africa

Replication paper 3ie 2022  
The authors of this paper replicated a landmark study by Hayes and colleagues (2019) on the HPTN 071 (PoPART) trial, which examined if a universal test and treatment program, along with a combination prevention intervention, could reduce HIV incidence in Zambia and South Africa. 

Treatment as prevention: A replication study on a universal test and treat cluster-randomized trial in South Africa from 2012–2016

Treatment as prevention: A replication study on a universal test and treat cluster-randomized trial in South Africa from 2012–2016

Replication paper 3ie 2022  

Authors of this paper replicated a landmark study by Iwuji and colleagues (2018) who examined the use of treatment as prevention (TaSP) trials for HIV-positive individuals in rural South Africa.

Treatment as prevention: a replication study on early antiretroviral therapy initiation and HIV-1 transmission

Treatment as prevention: a replication study on early antiretroviral therapy initiation and HIV-1 transmission

Replication paper 3ie 2020  
Eric Djimeu and Eleanor G Dickens conduct a replication of the HPTN 052 study by Cohen and colleagues that evaluates the impact of early initiation of antiretroviral therapy on rates of sexual transmission of HIV-1.

Biometric Smartcards and payment disbursement: a replication study of a state capacity-building experiment in India

Biometric Smartcards and payment disbursement: a replication study of a state capacity-building experiment in India

Replication paper 3ie 2019  
The National Rural Employment Guarantee Scheme and Social Security Pension are two of the largest employment programmes in Andhra Pradesh. Muralidharan and colleagues (2016) investigated the impacts of biometrically-authenticated payment infrastructure (Smartcards) on beneficiaries of the two employment programmes.

RPS22

Risk sharing and transaction costs: a replication study of evidence from Kenya’s mobile money revolution

Replication paper 3ie 2019  
This replication study starts with the twin strategies of push-button and pure replications of the original study. It then followed this up with various consistency and robustness checks, such as propensity score matching and the Tobit model specification.

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  • DOI : 10.23846/RPS0016

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